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    SCIENCE BEHIND THE NOOTROPIC STACK

    THE METAMEMORY® FORMULATION


    TABLE OF NOOTROPICS

    NOOTROPIC COMPOUNDS


    Lion's Mane

    Uridine

    BACOGNIZE®

    Alpha-GPC


    Pycnogenol®

    Huperzine-A

    BioPerine®

    DHA


    BRAIN VITAMINS


    VITAMIN b5

    Vitamin B9

    Vitamin b12

    Vitamin C


    Lion's Mane Mushroom Extract

    Serving Amount: 400 mg (1:1 Extract, Beta glucan minimum: 25%)

    Lion's Mane (Hericium erinaceus) is a mushroom that is popularly used in Chinese medicine with neuroprotective qualities, promoting nerve growth and synaptic plasticity. It has been shown to have a number of benefits—reducing symptoms of anxiety and depression, protecting against cancer, and improving memory. The mushroom also has anti-inflammatory and antioxidant properties, improving immune system function and overall health.

    Uridine Monophosphate

    Serving Amount: 300 mg (disodium salt)

    Uridine is a component of RNA and plays an integral role in central nervous system function. When combined with DHA, an omega-3 fatty acid that is essential for the development of the brain, and a choline source such as Alpha-GPC, the combination can stimulate the growth of synapses formed in the brain, called neurogenesis. Neurogenesis has been linked with improved cognitive function, particularly in learning and memory.

    BaCognize® Bacopa monnieri

    Serving Amount: 250mg

    Bacopa monnieri is an extensively studied ayurvedic herb that has been shown to have a wide range of benefits such as improving memory, mood, and learning in individuals. The primary way it works is through protecting the brain from free radicals and increasing levels of the neurotransmitter acetylcholine, as well as GABA and serotonin in smaller amounts. It also can reduce anxiety levels by reducing cortisol, promoting cognition especially in stressful situations. We use the standardized extract version, BaCognize®, which has shown efficacy through a randomized, placebo-controlled clinical trial.

    Alpha-GPC

    Serving Amount: 200 mg (L-Alpha glycerylphosphorylcholine)

    Alpha-GPC is one of the most bioavailable cholinergic compounds, crossing the blood brain barrier more easily than other forms of Choline. Choline, a nutrient found in common foods such as fish and eggs, is essential for function of the acetylcholine neurotransmitter, which improves memory, prevents cognitive decline, enhances neuron communication, and increases muscle control.

    FORMULATED WITH INGREDIENTS

    BACKED BY CLINICAL RESEARCH

    • Suntheanine®
    • Caffeine
    • Rhodiola
    • Ashwagandha
    • NALT
    • Sulbutiamine
    • L-Dopa + EGCG

    Suntheanine® (L-Theanine)

    Serving Amount: 200mg

    Suntheanine® L-Theanine promotes an alert state of relaxation without drowsiness, indicated by the increase in alpha brain waves and decrease in beta brain waves. L-Theanine works by increasing production of dopamine and serotonin to promote cognition, motivation and attention. We use Suntheanine® as the patented form of l-theanine which is a clinically researched, 100 percent pure L-isomer-theanine.

    CLINICALLY-BACKED RESEARCH


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Free Radical Research


    Forskolin and derivatives as tools for studying the role of cAMP. 

    Pharmazie


    Total of 457 studies on L-Theanine

    Caffeine

    Serving Amount: 100mg

    Caffeine is the most widely used psychoactive compound in the world. As a nootropic, it provides mental stimulation, alertness, and improved mood through modulation of the dopamine and adrenaline systems. Caffeine has also been shown to boost gene expression of brain-derived neurotrophic factor (BDNF), which can help protect against neurodegenerative diseases like Alzheimer's. The typical jittery energy from caffeine is balanced by the relaxed, alertness that l-theanine provides.

    CLINICALLY-BACKED RESEARCH


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Free Radical Research


    Forskolin and derivatives as tools for studying the role of cAMP. 

    Pharmazie


    Total of 457 studies on L-Theanine

    Rhodiola Rosea Extract

    Serving Amount: 200mg

    Rhodiola Rosea is a plant that has been shown to improve resilience to stress, increase alertness, and combat fatigue, especially in strenuous settings. It works by increasing the body's sensitivity to dopamine and serotonin, which are neurotransmitters involved in motivation, mood, focus, and pleasure. Rhodiola also increases AMPK, an enzyme that works as a master regulator of cellular energy homeostasis.

    CLINICALLY-BACKED RESEARCH


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Free Radical Research


    Forskolin and derivatives as tools for studying the role of cAMP. 

    Pharmazie


    Total of 457 studies on L-Theanine

    Ashwagandha Extract

    Serving Amount: 250mg (min. 5% withanolides)

    Ashwagandha has been used in Ayurvedic medicine for several thousand years and has been shown to help relieve stress, combat fatigue, and improve concentration. As an adaptogenic herb, it optimizes your body through normalizing blood sugar, enhancing insulin sensitivity as well as working as an antioxidant, protecting against inflammation.

    CLINICALLY-BACKED RESEARCH


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Free Radical Research


    Forskolin and derivatives as tools for studying the role of cAMP. 

    Pharmazie


    Total of 457 studies on L-Theanine

    NALT (N-Acetyl L-Tyrosine)

    Serving Amount: 250mg

    N-Acetyl L-Tyrosine is a more bioavailable form of L-Tyrosine, an amino acid that produces the neurotransmitters dopamine and norepinephrine. The compound has been shown to increase attention levels, heighten alertness, and improve memory. It is also very effective in stressful situations through improving mood and stress-resilience.

    CLINICALLY-BACKED RESEARCH


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Free Radical Research


    Forskolin and derivatives as tools for studying the role of cAMP. 

    Pharmazie


    Total of 457 studies on L-Theanine

    Sulbutiamine

    Serving Amount: 250mg

    Sulbutiamine was developed to address this issue as it passes through the blood-brain barrier more easily than natural thiamine (Vitamin B1), and as such has increased bioavailability. The compound has been shown to improve cholinergic and dopaminergic neurological transmissions within the brain resulting in a reduction in fatigue, increased motivation levels, improved memory, and enhanced learning ability.

    CLINICALLY-BACKED RESEARCH


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Free Radical Research


    Forskolin and derivatives as tools for studying the role of cAMP. 

    Pharmazie


    Total of 457 studies on L-Theanine

    L-Dopa (Mucuna Pruriens) // EGCG (Green Tea Extract)

    Serving Amount: 80mg (min. 40% L-Dopa) // 100mg

    L-Dopa, a compound from mucuna pruriens, is the last step in the conversion to dopamine, easily crossing the blood-brain barrier when taken as a supplement. Higher dopamine levels is associated with improved motivation levels as well as increased libido and enhanced memory retention. EGCG (from green tea extract) optimizes the efficiency of conversion to dopamine in the brain while reducing the peripheral side effects on the body.

    CLINICALLY-BACKED RESEARCH


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Journal of Nutrition


    Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro.

    Free Radical Research


    Forskolin and derivatives as tools for studying the role of cAMP. 

    Pharmazie


    Total of 457 studies on L-Theanine