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    metaBRAIN

    METABRAIN®

    61 reviews
    $127.85$98.95

    The METABRAIN® Box INCLUDES:*

    metaFOCUS® (30 day supply)
    metaMEMORY® (30 day supply)
    metaDRIVE® (30 day supply)
    Upgrade Your Brain, Upgrade Your Life (16-page booklet)*


    *Due to COVID-19 delays, we are temporarily shipping metaBRAIN without boxes & accessories. As a result we've provided a 10% discount to the price, from $109.85 to $98.85

    FEATURED IN

    Unlock Your Mind's Full Potential

    INTENSE FOCUS

    LASER-SHARP MEMORY

    UNSTOPPABLE DRIVE

    The metaBRAIN® box contains three nootropic supplements each with their own unique ingredient formulations, known as nootropic stacks.


    Each stack is centered around a fundamental cognitive pillar: focus for metaFOCUS®, memory for metaMEMORY®, and motivation for metaDRIVE®


    The three stacks are formulated with a collective total of 31 powerhouse nootropic ingredientsall in their clinically recommended dosages.

    Tools To Augment

    The Human Mind

    Formulated with the help of medical professionals to ensure that they were safe and effective synergistically.


    We only used ingredients backed by an extensive amount of published research to target all key brain pathways, producing the maximum cognitive benefits.


    After years of research, trials, and numerous iterations, we are now able to provide you the tools to augment the human mind.†

    An upgrade to your brain operating system.†

    Fully customizable, you can take the supplement(s) based on the mental areas you need optimized. Ultimately, integrating all three stacks provides the most profound enhancement to your brain. 

    Experience

    metaBRAIN®

    Three is Better Than One

    Reach Your Peak Mental Performance†

    METAFOCUS®

    Flow State • Processing Speed • Mental Clarity†

    BENEFITS

    • Heightened concentration and focus†

    • Ease of getting into flow state†

    • Improved mitochondrial health and energy production†

    • Improved mental processing speed and accuracy†

    • Reduction in intrusive thoughts and brain fog†

    COGNITIVE RATINGS

    FORMULATION


    NOOTROPIC COMPOUNDS


    ALCAR

    400 mg

    Luteolin

    400 mg

    Phenylalanine

    250 mg

    SerinAid®

    100 mg

    Cognizin®

    100 mg

    ALA

    100 mg

    Ginkgo Biloba

    70 mg

    Forskolin

    15 mg


    BRAIN VITAMINS


    Vitamin B5

    20 mg

    Vitamin B6

    5 mg

    Vitamin B9

    1 mg

    Vitamin B12

    600 mcg


    METAMEMORY®

    MEMORY • BRAIN HEALTh • Verbal Fluency†

    BENEFITS

    • Improved memory retention and recall†

    • Enhanced verbal fluency and word recall†

    • Heightened mental clarity and reduced brain-fog†

    • Improved brain health†

    • Reduced oxidative stress in the brain†

    COGNITIVE RATINGS

    FORMULATION


    NOOTROPIC COMPOUNDS


    Lion's Mane

    400 mg

    Uridine

    300 mg

    Bacopa

    250 mg

    Alpha-GPC

    100 mg

    Pine Bark

    100 mg

    DHA

    80 mg

    BioPerine®

    10 mg

    Huperzine-A

    40 mcg


    BRAIN VITAMINS


    Vitamin B5

    50 mg

    Vitamin B9

    1 mg

    Vitamin B12

    100 mcg

    Vitamin C

    45 mg


    METADRIVE®

    MOTIVATION • Smooth ENERGY • STRESS Resilience†

    BENEFITS

    • Focused energy without the jitters or crash†

    • Increased motivation and productivity levels†

    • Improved resilience to stress†

    • Heightened alertness and reduced fatigue†

    • Enhanced creativity from increase in alpha brain waves†

    COGNITIVE RATINGS

    FORMULATION


    NOOTROPIC COMPOUNDS


    Rhodiola

    300 mg

    NA-Tyrosine

    250 mg

    Sulbutiamine

    200 mg

    L-Theanine

    200 mg

    Ashwagandha

    180 mg

    Caffeine

    100 mg

    EGCG

    100 mg

    L-Dopa

    80 mg


    BRAIN VITAMINS


    Niacin

    40 mg

    Vitamin B6

    10 mg

    Vitamin B12

    200 mcg

    Vitamin D3

    1000 IU

    METABRAIN®

    INTENSE FOCUS LASER-SHarp MemoryUnstoppable Drive

    INTENSE FOCUS
    LASER-SHarp Memory
    Unstoppable Drive†

    Synergy For Total mental optimization

    Each stack in metaBRAIN® is effective on its own. But since the formulas work through mechanisms that are interconnected, you will notice synergy and efficacy when taking multiple stacks at once. 

    Supplementing with all three together provides the most comprehensive enhancement to your brain.


    More than just a Brain supplement

    Each metaBRAIN® box includes "Upgrade Your Brain, Upgrade Your Life", a 16-page booklet detailing how you can get the most out of metaBRAIN®. 


    The guide also introduces the branches for an upgraded life, which includes 16 foundational habits you can practice to reach your peak human potential—for both beginner and more experienced biohackers.

    UPGRADE YOUR BRAIN. UPGRADE YOUR LIFE.

    Peak performers. Peak results.

    Peak performers.

    Peak results.

    THE METABRAIN® DIFFERENCE

    THE METABRAIN®

    DIFFERENCE

    There's a ton of nootropic supplements out there. But most of them have minimally dosed ingredients, toxic fillers, cookie-cutter formulations, and/or no research to back them. Here's the metaBRAIN® difference:

    Full Formulation & Company Transparency

    We want you to know what you are putting in your body so we guarantee 100% transparency. This includes every aspect of our formulations such as disclosing all ingredient amounts, sourcing, and 3rd party testing. 


    Rest assured you're getting only the highest quality nootropic ingredients when taking metaBRAIN®.

    Customizable & Personalized protocol

    metaBRAIN® is customizable and each formula is effective on their own, with clinically-backed ingredients and proven synergies. In each box bundle, we provide you a comprehensive supplementation protocol based on your body-weight and cognitive requirements.


    Whether you need to optimize your focus, memory, drive, or all three, metaBRAIN® contains nootropics that do it all. Ultimately, supplementing with all three stacks together provides the most comprehensive enhancement to your mind.

    Clinically recommended Dosages

    Nootropics often have "proprietary blends" with ingredient dosages far below clinically recommended amounts. These blends are often packed into 1-3 capsules which do not have enough space to contain all the ingredients in their recommended amounts. 


    That's why we designed metaBRAIN® with three stacks, so that all ingredients within each formulation have clinically recommended dosages for full efficacy.

    Formulations fully Backed by Science 

    The collective metaBRAIN® formulation was created through extensive research and development by our team of biohackers, along with the help of doctors and naturopaths. All of our claims are backed by published research which can be found in the "references" section on the bottom of each product page.


    We will also be working with Cambridge Brain Sciences to conduct an observational study measuring the cognitive improvement of volunteers over a 6-week period. Details coming soon.

    60-Day Money-Back guarantee

    We're confident in the efficacy of metaBRAIN and its three stacks, so we have a 60-day money-back guarantee policy with no returns needed. All we ask is that you give it at least 2 weeks of consistent use for the stack(s) to experience the full effects. To learn more go to our return policy page.


    OUTSOURCE YOUR COGNITIVE ENHANCEMENT

    COST-EFFECTIVE MENTAL OPTIMIZATION


    METAFOCUS®

    METAMEMORY®

    METADRIVE®

    METABRAIN®

    MARKET PRICE

    IF BOUGHT INDIVIDUALLY*

    METAFOCUS®

    METAMEMORY®

    METADRIVE®

    METABRAIN®

    META
    FOCUS
    META
    MEMORY
    META
    DRIVE
    META
    BRAIN

    $205.50

    $243.89

    $182.64

    $562.05


    OUR PRICE

    PER MONTH

    META
    FOCUS
    META
    MEMORY
    META
    DRIVE
    META
    BRAIN

    METAFOCUS®

    METAMEMORY®

    METADRIVE®

    METABRAIN®

    $36.42

    $35.40

    $36.84

    $93.37

    * These prices are based on the prices of the top supplements sold on Amazon with similar quality to the ingredients in each of the metaBRAIN® formulas.

    Who really wants to take 31+ different supplements at the expensive price of $562 to enhance your brain function? We make it easy for you with a cost-effective (and time-saving) solution to get mentally optimized. 


    You also have peace of mind knowing that all the nootropic ingredients within the metaBRAIN® supplements are of the highest quality, backed by extensive research. 

    31 powerhouse Ingredients.

    the convenience of 3 supplements.

    "Man will not wait passively for millions of years before evolution offers him a better brain."


    CORNELIU E GIURGEA

    "THE FATHER OF NOOTROPICS"

    Dr. Helen Okoye M.D.

    NATIONAL INSTITUTES OF HEALTH (NIH)

    CLINICAL AND RESEARCH FELLOW

    The nootropics supplements industry is on the rise. With companies selling brain-enhancement pills sprouting up from all over the country, it’s hard to distinguish which are actually safe and effective. In all my years working as a medical professional, I’ve seen many nootropic products. However, Nuoptimal’s metaBRAIN stands out.


    The clinically-backed supplement holistically covers all components of cognitive enhancement. Each supplement in the metaBRAIN box is formulated to be safe, affordable, and most importantly, effective.

    Dr. Helen Okoye M.D.

    NATIONAL INSTITUTES OF HEALTH (NIH)

    CLINICAL AND RESEARCH FELLOW


    Customer Reviews
    4.7 Based on 61 Reviews
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    Filter Reviews:
    RF
    09/25/2020
    Ryan F.
    United States United States
    Great product

    Highly recommend

    TG
    09/19/2020
    Thomas G.
    United States United States
    The first nootropic I've tried that actually works!

    I've tried a couple other of the big names in the area of nootropics, both of which had no effect, so heading into this I had low expectations. I used the full stack, Focus, Memory, and Drive, and after just a week I noticed a difference. I used to get a large lull in energy after work and found it hard to do more work throughout the rest of my day, but this keeps me equally focused and energized throughout my whole day. Plus, there is only 100mg of caffeine in the whole stack, so you don't get that jittery comedown, that cheaper nooprics often have. So if you're looking for something to help keep you focused and in top shape throughout the day, this is the way to go.

    JM
    09/01/2020
    John M.
    United States United States
    Good Stuff!

    Solid. Good product.

    KW
    08/28/2020
    Keith W.
    United States United States

    Great product I have more energy and focus

    RW
    08/15/2020
    Rachel W.
    United States United States
    Natural boost

    Recently received my second monthly order, and I’m hooked! I’ve noticed a definite improvement in my motivation to get tasks done, and ability to concentrate on tasks at hand. My productivity at work is consistent, without those “blah” days of just trying to make it through the day. My mood is more balanced lately too, which I hadn’t even noticed really until looking back and thinking, “wow, I just feel good.” Highly recommend! And stick with it. For me, personally, effects took a couple weeks to acclimate.

    Patents & Trademarks

    Cognizin® is a registered trademark of KYOWA HAKKO BIO CO., LTD.

    SerinAid® is a registered trademark of Chemi Nutra. SerinAid is protected under U.S. patent numbers 5,700,668, 6,492,146, 6,645,742, 6,673,378, and 8,124,594. 

    BioPerine® is a registered trademark of Sabinsa Corporation.

    Memory Retention

    1. Kumar, Navneet et al. “Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial.” Evidence-based complementary and alternative medicine : eCAM vol. 2016 (2016): 4103423. doi:10.1155/2016/4103423
    2. Ratto, Daniela et al. “Hericium erinaceus Improves Recognition Memory and Induces Hippocampal and Cerebellar Neurogenesis in Frail Mice during Aging.” Nutrients vol. 11,4 715. 27 Mar. 2019, doi:10.3390/nu11040715
    3. Kumar, Hemant et al. “Promising therapeutics with natural bioactive compounds for improving learning and memory--a review of randomized trials.” Molecules (Basel, Switzerland) vol. 17,9 10503-39. 3 Sep. 2012, doi:10.3390/molecules170910503
    4. Brandalise, Federico et al. “Dietary Supplementation of Hericium erinaceusIncreases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice.” Evidence-based complementary and alternative medicine : eCAM vol. 2017 (2017): 3864340. doi:10.1155/2017/3864340
    5. Micheau J, Durkin TP, Destrade C, Rolland Y, Jaffard R. Chronic administration of sulbutiamine improves long term memory formation in mice: possible cholinergic mediation. Pharmacol Biochem Behav. 1985 Aug;23(2):195-8. PubMed PMID: 4059305.
    6. Lynch MA. Long-term potentiation and memory. Physiol Rev. 2004 Jan;84(1):87-136. Review. PubMed PMID: 14715912. 

    Attention-Span & Focus

    1. Ahn, James et al. “Natural Product-Derived Treatments for Attention-Deficit/Hyperactivity Disorder: Safety, Efficacy, and Therapeutic Potential of Combination Therapy.” Neural plasticity vol. 2016 (2016): 1320423. doi:10.1155/2016/1320423
    2. McGlade E, Agoston AM, DiMuzio J, Kizaki M, Nakazaki E, Kamiya T, Yurgelun-Todd D. The Effect of Choline Supplementation on Motor Speed and Attention in Adolescent Males. J Atten Disord. 2019 Jan;23(2):121-134. doi: 10.1177/1087054715593633. Epub 2015 Jul 15. PubMed PMID: 26179181.
    3. Food and Nutrition Sciences et al. "Improved Attentional Performance Following Choline Administration in Healthy Adult Women" 2012, 3, 769-773. doi:10.4236/fns.2012.36103 Published Online June 2012
    4. Kahathuduwa, Chanaka et al. “L-theanine and Caffeine Improve Sustained Attention, Impulsivity and Cognition in Children with Attention Deficit Hyperactivity Disorders by Decreasing Mind Wandering (OR29-04-19).” Current Developments in Nutrition vol. 3,Suppl 1 nzz031.OR29-04-19. 13 Jun. 2019, doi:10.1093/cdn/nzz031.OR29-04-19
    5. Bloch, Michael H, and Jilian Mulqueen. “Nutritional supplements for the treatment of ADHD.” Child and adolescent psychiatric clinics of North America vol. 23,4 (2014): 883-97. doi:10.1016/j.chc.2014.05.002

    Planning & Reasoning

    1. Gomez-Ramirez M, Kelly SP, Montesi JL, Foxe JJ. The effects of L-theanine on alpha-band oscillatory brain activity during a visuo-spatial attention task. Brain Topogr. 2009 Jun;22(1):44-51. doi: 10.1007/s10548-008-0068-z. Epub 2008 Oct 9. PubMed PMID: 18841456.
    2. Kurniawan, Irma Triasih et al. “effort-based decision making.” Frontiers in neuroscience vol. 5 81. 21 Jun. 2011, doi:10.3389/fnins.2011.00081
    3. Picciotto, Marina R et al. “Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior.” Neuron vol. 76,1 (2012): 116-29. doi:10.1016/j.neuron.2012.08.036

    Mental Clarity

    1. Dietz C, Dekker M. Effect of Green Tea Phytochemicals on Mood and Cognition.Curr Pharm Des. 2017;23(19):2876-2905. doi: 10.2174/1381612823666170105151800.Review. PubMed PMID: 28056735.
    2. Gestuvo, Mk, and Ww Hung. “Common dietary supplements for cognitive health.” Aging health vol. 8,1 (2012): 89-97. doi:10.2217/AHE.11.92
    3. Theoharides, Theoharis C et al. “Brain "fog," inflammation and obesity: key aspects of neuropsychiatric disorders improved by luteolin.” Frontiers in neuroscience vol. 9 225. 3 Jul. 2015, doi:10.3389/fnins.2015.00225

    Motivation & Productivity

    1. Westbrook, Andrew, and Todd S Braver. “Does Double Duty in Motivating Cognitive Effort.” Neuron vol. 89,4 (2016): 695-710. doi:10.1016/j.neuron.2015.12.029
    2. Bloemendaal, Mirjam et al. “Neuro-Cognitive Effects of Acute Tyrosine Administration on Reactive and Proactive Response Inhibition in Healthy Older Adults.” eNeuro vol. 5,2 ENEURO.0035-17.2018. 30 Apr. 2018, doi:10.1523/ENEURO.0035-17.2018
    3. Trovero F, Gobbi M, Weil-Fuggaza J, Besson MJ, Brochet D, Pirot S. Evidence for a modulatory effect of sulbutiamine on glutamatergic cortical transmissions in the rat brain. Neurosci Lett. 2000 Sep 29;292(1):49-53. PubMed PMID: 10996447.
    4. Veĭn AM, Fedotova AV, Gordeev SA. [Use of enerion in psychovegetative syndrome with pronounced asthenia]. Zh Nevrol Psikhiatr Im S S Korsakova. 2003;103(10):36-9. Russian. PubMed PMID: 14628585.

    Enhanced Creativity

    1. Gomez-Ramirez M, Kelly SP, Montesi JL, Foxe JJ. The effects of L-theanine on alpha-band oscillatory brain activity during a visuo-spatial attention task. Brain Topogr. 2009 Jun;22(1):44-51. doi: 10.1007/s10548-008-0068-z. Epub 2008 Oct 9. PubMed PMID: 18841456.
    2. Fink, Andreas, and Mathias Benedek. “EEG alpha power and creative ideation.” Neuroscience and biobehavioral reviews vol. 44,100 (2014): 111-23. doi:10.1016/j.neubiorev.2012.12.002
    3. Zabelina, Darya L et al. “and the Creative Mind: Individual Differences in Creativity Are Predicted by Interactions between Genes DAT and COMT.” PloS one vol. 11,1 e0146768. 19 Jan. 2016, doi:10.1371/journal.pone.0146768

    Improved Brain Health

    1. Ratto, Daniela et al. “Hericium erinaceus Improves Recognition Memory and Induces Hippocampal and Cerebellar Neurogenesis in Frail Mice during Aging.” Nutrients vol. 11,4 715. 27 Mar. 2019, doi:10.3390/nu11040715
    2. Li, I-Chen et al. “Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines.” Behavioural neurology vol. 2018 5802634. 21 May. 2018, doi:10.1155/2018/5802634
    3. Iravani, S, and B Zolfaghari. “Pharmaceutical and nutraceutical effects of Pinus pinaster bark extract.” Research in pharmaceutical sciences vol. 6,1 (2011): 1-11.
    4. Wurtman, Richard J. “A nutrient combination that can affect synapse formation.” Nutrients vol. 6,4 1701-10. 23 Apr. 2014, doi:10.3390/nu6041701 
    5. Kwon, Hyun Jung et al. “Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus.” Laboratory animal research vol. 34,4 (2018): 239-247. doi:10.5625/lar.2018.34.4.239
    6. Silveri MM, Dikan J, Ross AJ, Jensen JE, Kamiya T, Kawada Y, Renshaw PF, Yurgelun-Todd DA. Choline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopy. NMR Biomed. 2008 Nov;21(10):1066-75. doi: 10.1002/nbm.1281. PubMed PMID: 18816480.

    Mood & Stress-Relief

    1. Institute of Medicine (US) Committee on Military Nutrition Research; Marriott BM, editor. Food Components to Enhance Performance: An Evaluation of Potential Performance-Enhancing Food Components for Operational Rations. Washington (DC): National Academies Press (US); 1994. 20, Effects of Caffeine on Cognitive Performance, Mood, and Alertness in Sleep-Deprived Humans.
    2. Antidepressant-like effects of uridine and omega-3 fatty acids are potentiated by combined treatment in rats Carlezon, William A. et al. Biological Psychiatry, Volume 57, Issue 4, 343 - 350
    3. White, David J et al. “Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.” Nutrients vol. 8,1 53. 19 Jan. 2016, doi:10.3390/nu8010053
    4. Chandrasekhar, K et al. “A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.” Indian journal of psychological medicine vol. 34,3 (2012): 255-62. doi:10.4103/0253-7176.106022
    5. Pratte, Morgan A et al. “An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera).” Journal of alternative and complementary medicine (New York, N.Y.) vol. 20,12 (2014): 901-8. doi:10.1089/acm.2014.0177
    6. Yoto, Ai et al. “Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses.” Journal of physiological anthropology vol. 31,1 28. 29 Oct. 2012, doi:10.1186/1880-6805-31-28
    7. Jongkees BJ, Hommel B, Kühn S, Colzato LS. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review. J Psychiatr Res. 2015 Nov;70:50-7. doi: 10.1016/j.jpsychires.2015.08.014. Epub 2015 Aug 25. Review. PubMed PMID: 26424423.

    Verbal Fluency

    1. Glade MJ, Smith K. Phosphatidylserine and the human brain. Nutrition. 2015 Jun;31(6):781-6. doi: 10.1016/j.nut.2014.10.014. Epub 2014 Nov 4. Review. PubMed PMID: 25933483.
    2. Peter, Jessica et al. “Contribution of the Cholinergic System to Verbal Memory Performance in Mild Cognitive Impairment.” Journal of Alzheimer's disease : JAD vol. 53,3 (2016): 991-1001. doi:10.3233/JAD-160273
    3. Hasselmo, Michael E. “The role of acetylcholine in learning and memory.” Current opinion in neurobiology vol. 16,6 (2006): 710-5. doi:10.1016/j.conb.2006.09.002

    Energy & Alertness

    1. Institute of Medicine (US) Committee on Military Nutrition Research; Marriott BM, editor. Food Components to Enhance Performance: An Evaluation of Potential Performance-Enhancing Food Components for Operational Rations. Washington (DC): National Academies Press (US); 1994. 20, Effects of Caffeine on Cognitive Performance, Mood, and Alertness in Sleep-Deprived Humans.
    2. Sevim S, Kaleağası H, Taşdelen B. Sulbutiamine shows promising results in reducing fatigue in patients with multiple sclerosis. Mult Scler Relat Disord. 2017 Aug;16:40-43. doi: 10.1016/j.msard.2017.05.010. Epub 2017 Jun 9. PubMed PMID: 28755683.
    3. Tiev KP, Cabane J, Imbert JC. [Treatment of chronic postinfectious fatigue: randomized double-blind study of two doses of sulbutiamine (400-600 mg/day) versus placebo]. La Revue de Medecine Interne. 1999 Oct;20(10):912-918. DOI: 10.1016/s0248-8663(00)80096-x.
    4. Harpaz E, Tamir S, Weinstein A, Weinstein Y. The effect of caffeine on energy balance. J Basic Clin Physiol Pharmacol. 2017 Jan 1;28(1):1-10. doi: 10.1515/jbcpp-2016-0090. Review. PubMed PMID: 27824614.