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    metaMEMORY

    METAMEMORY®

    $41.65

    Sharp Memory, Sharper Mind

    Perfect memory recall and mental clarity—some are born with it, and others have to obtain it. That’s where metaMEMORY® comes in. Master memory recollection and eradicate brain fog.†


    Formulated With Optimal Ingredients

    Formulated with 8 powerhouse nootropics including Lion's mane, Bacopa monnieriAlpha-GPC, and 4 brain vitamins to support improved memory retention, mental clarity, and overall brain health.


    Designed to Support Key Mental Areas

    short & long-term memory Retention†

    Heightened Mental clarity & Reduced Fog†

    Improved Brain health†

    Improved Verbal Fluency & Word Recall†


    THE KEYS TO LASER-SHARP

    MEMORY RETENTION

    Neuroplasticity and neurogenesis help rewire and rebuild your neural circuitry. They help improve long-term brain health and heighten cognition–specifically memory retention and learning.[14]

    NEUROPLASTICITY noun

    The ability of the brain to adapt in structure. This is how permanent learning takes place, such as through a new language or playing an instrument.

    NEUROGENESIS noun

    The growth of new neurons in the brain. Neurogenesis plays a vital role in learning, memory formation, and long-term brain health.

    metaMEMORY® is formulated to increase BDNF (brain-derived neurotrophic factor), NGF (nerve growth factor), and reduce oxidative stress–improving neuroplasticity and neurogenesis in the brain.


    Higher levels of BDNF and NGF may improve mood, brain health, and memory.[15] Studies show that reducing oxidative stress associated with free radicals supports healthy brain function.[16]

    Our FORMULA OPTIMIZES MEMORY THROUGH THREE MAIN PROCESSES

    FEATURED IN

    Herbal Nutrients for Long-Term Brain Health

    metaMEMORY® contains an all-natural blend of powerful ayurvedics and herbs that have been used by many cultures for centuries. This means that whenever you take metaMEMORY®, you are supplementing with extensively researched ingredients that are proven to improve long-term brain health and function.

    Lion's Mane mushroom

    from hericium erinaceus

    BACOPA MONNIERI

    from waterhyssop

    PYCnogenol

    from maritime pine bark

    HUPERZINE-A

    from huperzia serrata

    Bioperine Black Pepper

    from piper nigrum

    DHA

    from algae

    Perfect the Art of Communication


    “The ability to assemble one’s thoughts and to speak on the spur of the moment is even more important, in some ways, than the ability to speak only after lengthy and laborious preparation.”

    DALE CARNEGIE, AUTHOR


    Whether you’re leading a team, socializing, or networking, articulation and verbal communication skills are crucial.


    metaMEMORY® is formulated with Huperzine-A, an ingredient that can help recall specific words and promote clearer thinking.[21] This is combined with Bacopa monnieri and Lion’s mane mushroom, which have been shown to reduce stress and improve short and long term memory–so you can speak with confidence.[22] [23]

    Conquer your next presentation with the eloquence of a professional orator.†



    THE SCIENCE BEHIND THE URIDINE STACK

    The Uridine stack consists of Uridine, DHA, a choline source (alpha-GPC), and vitamins B9 and B12—all within metaMEMORY® in the clinically recommended dosages. The uridine stack has synergy to enhance memory and learning[24] as well as improve mood.[25]


    Through the creation of new dopamine receptors, the stack combines efficaciously with compounds that modulate the neurotransmitter dopamine—contained within the other two stacks of metaBRAIN.

    URIDINE'S MECHANISM OF ACTION

    • Supports growth of neural tissue. Having a well-connected and healthy set of dendritic pathways in the brain can improve both mood and cognition.[26]

    • Promotes the creation of new dopamine receptors in the brain through activation of the D1 and D2 receptors.[27]

    FORMULATED WITH INGREDIENTS BACKED BY CLINICAL RESEARCH


    8 NOOTROPIC COMPOUNDS


    LION's Mane

    400 mg (Beta glucan >25%)

    Lion's mane is a mushroom with neuroprotective qualities and has been shown to have a number of benefits—improving memory, reducing stress, and aiding in overall brain health.[1] [2]

    Uridine

    300 mg (disodium salt)

    Uridine is a component of RNA & plays an integral role in central nervous system function. It has been shown to stimulate the growth of synapses, called neurogenesis, leading to improved memory and brain function.[3]

    BACOPA MONNIERI

    250 mg

    Bacopa Monnieri is a powerhouse ayurvedic herb that has been extensively studied and used throughout history. It has a wide range of benefits such as improving memory, mood, and learning as well as reducing stress.[4]

    Alpha-Gpc

    200 mg (50% alpha-GPC)

    Alpha-GPC is one of the most bioavailable cholinergic compounds. It has been shown to improve memory, enhance neuron communication, and increase muscle control.[5]

    Pine Bark Extract

    100 mg (95% proanthocyanidins)

    100 mg (95%)

    Pine bark extract is a nootropic compound which has been shown to promote blood flow to the brain as well as improve working memory, sustained attention, and executive functioning.[6]

    Huperzine-A

    80 mcg (huperzia serrata)

    Huperzine-A prevents the breakdown of the neurotransmitter acetylcholine. It is has been shown to improve memory retention and learning.[7]

    BioPerine®

    10 mg

    BioPerine® is a patented source of piperine which is extracted from black pepper. It has been shown to increase the absorption of a number of nootropic compounds and improve cognitive function.[8]

    DHA

    80 mg

    DHA is an omega-3 fatty acid that is essential for the development of the brain. It has been shown to support the growth of new brain cells and higher levels of DHA are correlated with improved memory & executive function.[9]


    4 BRAIN VITAMINS


    Vitamin b5

    50 mg (pantothenic acid)

    B5 is crucial for converting cholinergic compounds such as Alpha-GPC into acetylcholine, the neurotransmitter responsible for focus, memory, and learning.[10]

    Vitamin b9

    400 mcg (folic acid)

    B9 is a crucial component for the uridine stack in the formation of new synapses between neurons in the brain. It also plays an integral role in improving mood and cognitive function.[11]

    Vitamin b12

    100 mcg (methylcobalamin)

    B12 is crucial for the synthesis of the brain neurotransmitters dopamine, serotonin, and GABA. Optimizing these neurotransmitters ultimately improves our mood, energy, and stress levels.[11]

    Vitamin C

    600 mcg (ascorbic acid)

    Vitamin C helps protect the brain from oxidative stress. Consistent supplementation can improve mood and reduce stress.[12] [13]

    Unlock Your Mind's Full Potential


    metaFOCUS® is just one component of the optimal mental performance equation. Tap into your true potential and comprehensively upgrade your brain with metaBRAIN®, a three-supplement box designed for peak mental performance.


    Formulated with a collective 31 nootropic ingredients, the three supplements in the metaBRAIN® box complement each other, sharpening focus, enhancing memory recollection, and igniting drive.†

    Experience Intense FocusLaser-Sharp MemoryUnstoppable Drive.


    Upgrade Your Brain, Upgrade Your Life.

    The metaBRAIN® box includes "Upgrade Your Brain, Upgrade Your Life", a 16-page booklet that contains a comprehensive supplementation protocol based on your body-weight and cognitive requirements.


    The booklet also introduces the branches for an upgraded life, which includes 16 foundational habits you can practice to reach your peak human potential—for both beginner and more experienced biohackers.

    METABRAIN® IS Designed to Optimize:†

    CUSTOMER REVIEWS

    Patents & Trademarks

    BioPerine® is a registered trademark of Sabinsa Corporation.


    REFERENCES

    [1] Ratto, Daniela et al. “Hericium erinaceus Improves Recognition Memory and Induces Hippocampal and Cerebellar Neurogenesis in Frail Mice during Aging.” Nutrients vol. 11,4 715. 27 Mar. 2019, doi:10.3390/nu11040715

    [2] Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki K.Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. BiomedRes. 2010 Aug;31(4):231-7. PubMed PMID: 20834180.

    [3] Arpad Dobolyi, Gabor Juhasz, Zsolt Kovacs and Julianna Kardos, “ Uridine Function in the Central Nervous System”, Current Topics in Medicinal Chemistry (2011) 11: 1058. https://doi.org/10.2174/156802611795347618

    [4] Kumar, Navneet et al. “Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial.” Evidence-based complementary and alternative medicine : eCAM vol. 2016 (2016): 4103423. doi:10.1155/2016/4103423

    [5] Parker, Adam G et al. “The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility.” Journal of the International Society of Sports Nutrition vol. 12,Suppl 1 P41. 21 Sep. 2015, doi:10.1186/1550-2783-12-S1-P41

    [6] Simpson, Tamara et al. “Assessing the Efficacy and Mechanisms of Pycnogenol® on Cognitive Aging From In Vitro Animal and Human Studies.” Frontiers in pharmacology vol. 10 694. 3 Jul. 2019, doi:10.3389/fphar.2019.00694

    [7] Qian, Zhong Ming, and Ya Ke. “Huperzine A: Is it an Effective Disease-Modifying Drug for Alzheimer's Disease?.” Frontiers in aging neuroscience vol. 6 216. 19 Aug. 2014, doi:10.3389/fnagi.2014.00216

    [8] Wattanathorn J, et al (2008). Piperine, the potential functional food for mood and cognitive disorders. Food Chem Toxicol, 46(9):3106-10. doi: 10.1016/j.fct.2008.06.014

    [9] Lauritzen, Lotte et al. “DHA Effects in Brain Development and Function.” Nutrients vol. 8,1 6. 4 Jan. 2016, doi:10.3390/nu8010006

    [10] Patassini, Stefano et al. “Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington's Disease.” Metabolites vol. 9,6 113. 11 Jun. 2019, doi:10.3390/metabo9060113

    [11] Kennedy, David O. “B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review.” Nutrients vol. 8,2 68. 27 Jan. 2016, doi:10.3390/nu8020068

    [12] Kawashima, Akihiro et al. “Vitamin C Induces the Reduction of Oxidative Stress and Paradoxically Stimulates the Apoptotic Gene Expression in Extravillous Trophoblasts Derived From First-Trimester Tissue.” Reproductive sciences (Thousand Oaks, Calif.) vol. 22,7 (2015): 783-90. doi:10.1177/1933719114561561

    [13] Suh, Sang-Yeon et al. “Intravenous vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial.” Nutrition journal vol. 11 7. 20 Jan. 2012, doi:10.1186/1475-2891-11-7

    [14] Shaffer, Joyce. “Neuroplasticity and Clinical Practice: Building Brain Power for Health.” Frontiers in psychology vol. 7 1118. 26 Jul. 2016, doi:10.3389/fpsyg.2016.01118

    [15] Kowiański, Przemysław et al. “BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity.” Cellular and molecular neurobiology vol. 38,3 (2018): 579-593. doi:10.1007/s10571-017-0510-4

    [16] Budni, Josiane et al. “The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease.” Aging and disease vol. 6,5 331-41. 1 Oct. 2015, doi:10.14336/AD.2015.0825

    [17] Banerjee, Ritabrata et al. “Chronic administration of bacopa monniera increases BDNF protein and mRNA expressions: a study in chronic unpredictable stress induced animal model of depression.” Psychiatry investigation vol. 11,3 (2014): 297-306. doi:10.4306/pi.2014.11.3.297

    [18] Kidd PM. Integrated brain restoration after ischemic stroke--medical management, risk factors, nutrients, and other interventions for managing inflammation and enhancing brain plasticity. Altern Med Rev. 2009 Mar;14(1):14-35. Review. PubMed PMID: 19364191.

    [19] Tang LL, Wang R, Tang XC. Effects of huperzine A on secretion of nerve growth factor in cultured rat cortical astrocytes and neurite outgrowth in rat PC12 cells. Acta Pharmacol Sin. 2005 Jun;26(6):673-8. PubMed PMID: 15916732.

    [20] Ko JW, Lee IC, Park SH, Moon C, Kang SS, Kim SH, Kim JC. Protective effects ofpine bark extract against cisplatin-induced hepatotoxicity and oxidative stressin rats. Lab Anim Res. 2014 Dec;30(4):174-80. doi: 10.5625/lar.2014.30.4.174.Epub 2014 Dec 24. PubMed PMID: 25628728; PubMed Central PMCID: PMC4306705.

    [21] Qian ZM and Ke Y (2014) Huperzine A: is it an effective disease-modifying drug for Alzheimer’s disease? Front. Aging Neurosci. 6:216. doi: 10.3389/fnagi.2014.00216

    [22] Kumar, Navneet et al. “Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial.” Evidence-based complementary and alternative medicine : eCAM vol. 2016 (2016): 4103423. doi:10.1155/2016/4103423

    [23] Ratto, Daniela et al. “Hericium erinaceus Improves Recognition Memory and Induces Hippocampal and Cerebellar Neurogenesis in Frail Mice during Aging.” Nutrients vol. 11,4 715. 27 Mar. 2019, doi:10.3390/nu11040715

    [24] Holguin, Sarah et al. “Dietary uridine enhances the improvement in learning and memory produced by administering DHA to gerbils.” FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 22,11 (2008): 3938-46. doi:10.1096/fj.08-112425

    [25] Antidepressant-like effects of uridine and omega-3 fatty acids are potentiated by combined treatment in rats Carlezon, William A. et al. Biological Psychiatry, Volume 57, Issue 4, 343 - 350

    [26] Wurtman, Richard J. “A nutrient combination that can affect synapse formation.” Nutrients vol. 6,4 1701-10. 23 Apr. 2014, doi:10.3390/nu6041701

    [27] Cansev, Mehmet et al. “Restorative effects of uridine plus docosahexaenoic acid in a rat model of Parkinson's disease.” Neuroscience research vol. 62,3 (2008): 206-9. doi:10.1016/j.neures.2008.07.005