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    metaPRODUCTIVITY
    metaPRODUCTIVITY

    METAPRODUCTIVITY®

    $73.85

    Focus Meets Drive

    metaPRODUCTIVITY was made for long days and busy workweeks. metaDRIVE enhances the benefits of metaFOCUS allowing you to conquer anything and everything the day throws your way. Experience productivity on a whole new level.


    METAPRODUCTIVITY INCLUDES:

    metaFOCUS® (30 day supply)

    metaDRIVE®(30 day supply)


    Designed to Support Key Mental Areas

    Improved attention-span & focus†

    Mental Clarity & Faster Processing Speeds†

    Calm, Focused Energy with No crash†

    Increased motivation & Productivity levels†


    Transform Your Productivity

    Combining our two most powerful formulations, creating the ultimate nootropic stack for heightened cognitive performance.


    Woke up feeling groggy? Struggling to get out of the afternoon slump? Can’t seem to focus? Break out of your shell with extreme productivity, energy, and concentration.

    METAFOCUS®

    Flow state in a bottle.

    metaFOCUS® helps the brain achieve an optimal state of consciousness where an individual utilizes their skills to the utmost. In this state, individuals feel, perform, and focus at their best.


    METADRIVE®

    Fuel to reach peak performance.

    metaDRIVE® is geared towards amplifying a key neurotransmitter. Also known as the “chemical of reward", optimal levels of concentration to make us feel motivated, focused, and accomplished.

    METAFOCUS®

    Cognitive Ratings

    FEATURED IN

    The Ingredients Breakdown

    • metaFOCUS Formulation
    • metaDRIVE Formulation

    8 NOOTROPIC COMPOUNDS


    Artichoke Extract

    400 mg (5% cynarins)

    Luteolin, found in artichoke extract inhibits PDE4, which increases cAMP. Higher cAMP levels is correlated with improving learning, memory, and mood.[1]

    FORSKOLIN

    15 mg (20% forskolii)

    Forskolin naturally increases cAMP levels synergizing with luteolin to strengthen neural synapses, also known as long-term potentiation improving cognitive function over time.[2]

    Acetyl-l-carnitine

    400 mg

    ALCAR improves mitochondrial function and increase levels of noradrenaline, associated with focus and alertness. It has also been shown to be effective in reducing brain fog.[3]

    SERinaid®

    100 mg (PhosphatidylSerine)

     PhosphatidylSerine has been shown to improve memory & increase concentration. It can also lower cortisol, reducing stress & intrusive thoughts.[4]

    Artichoke Extract

    400 mg (5% cynarins)

    Luteolin, found in artichoke extract inhibits PDE4, which increases cAMP. Higher cAMP levels is correlated with improving learning, memory, and mood.[1]

    FORSKOLIN

    15 mg (20% forskolii)

    Forskolin naturally increases cAMP levels synergizing with luteolin to strengthen neural synapses, also known as long-term potentiation improving cognition over time.[2]

    Acetyl-l-carnitine

    400 mg

    ALCAR improves mitochondrial function and increase levels of noradrenaline, associated with focus and alertness. It has also been shown to be effective in reducing brain fog.[3]

    SERinaid®

    100 mg (PhosphatidylSerine)

     PhosphatidylSerine has been shown to reduce cognitive decline, improve memory & reduce symptoms of ADHD. It can also lower cortisol, reducing anxiety & intrusive thoughts.[4]

    GinkGO BILOBA

    70 mg (24% glycosides)

    Ginkgo Biloba is an antioxidant-rich herb that has been shown to increase cerebral blood flow, improving brain health and cognition, specifically attention and memory recall.[5]

    DL-PHENYLALANINE

    250 mg

    Phenylalanine is an amino acid that is a building block for the neurotransmitter dopamine. Higher dopamine levels in the brain is correlated with improved attention-span, mood, and motivation.[6]

    Cognizin®

    100 mg

    Citicoline modulates levels of the acetylcholine neurotransmitter, which helps nerves to communicate, increase attention-span, memory capacity, and prevent cognitive decline.[7]

    Alpha-Lipoic Acid

    100 mg (thiotic acid)

    ALA is a mitochondrial compound that works similarly to ALCAR involved in energy metabolism and the production of acetylcholine. It has been shown to boost cellular energy and protect brain neurons.[8]

    GinkGO BILOBA

    70 mg (24% glycosides)

    Ginkgo Biloba is an antioxidant-rich herb that has been shown to increase cerebral blood flow, improving brain health, attention-span, and memory recall.[5]

    DL-PHENYLALANINE

    250 mg

    Phenylalanine is an amino acid that has been shown to produce improved attention-span, mood, and motivation.[6]

    Cognizin®

    100 mg

    Cognizin® modulates levels of the acetylcholine neurotransmitter, which helps nerves to communicate, increase attention-span, and memory capacity.[7]

    Alpha-Lipoic Acid

    100 mg (thiotic acid)

    ALA is a mitochondrial compound that works similarly to ALCAR involved in energy metabolism and the production of acetylcholine.[8]


    4 Brain Vitamins


    Vitamin b5

    20 mg (pantothenic acid)

    Essential for converting cholinergic nootropics into acetylcholine, the neurotransmitter responsible for focus, memory, and learning.[9]

    Vitamin b6

    5 mg (pyridoxal 5’-phosphate)

    An essential vitamin which is required for the biosynthesis of several key neurotransmitters. We use P5P, one of the most bioactive forms of B6.[9]

    Vitamin b9

    1 mg (folic acid)

    B9 is required for the synthesis of key neurotransmitters such as serotonin, playing an integral role in improving mood and cognitive function.[9]

    Vitamin b12

    600 mcg (methylcobalamin)

    B12 is crucial for the synthesis of key neurotransmitters. Optimizing these neurotransmitters improve our mood, energy, and stress levels.[9]


    8 NOOTROPIC COMPOUNDS


    L-Theanine

    200 mg

    L-Theanine promotes an alert state of relaxation without drowsiness, indicated by the increase in alpha brain waves and decrease in beta brain waves.[1]

    Caffeine

    100 mg

    Caffeine is the most widely used psychoactive compound in the world. As a nootropic, it provides mental stimulation, alertness, and improved mood.[2]

    Rhodiola Rosea

    300 mg (3% salidroside)

    Rhodiola rosea is a plant that has been shown to improve resilience to stress, increase alertness, and combat fatigue, especially in strenuous settings.[3]

    Ashwagandha

    180 mg (>5% withanolides)

    Ashwagandha has been used in Ayurvedic medicine for several thousand years and has been shown to help relieve stress, combat fatigue, and improve concentration.[4]

    N-Acetyl L-Tyrosine

    250 mg

    N-Acetyl L-Tyrosine is a more bioavailable form of L-Tyrosine, an amino acid. The compound has been shown to increase attention, heighten alertness, and improve stress-resilience.[5]

    Sulbutiamine

    200 mg

    Sulbutiamine has been shown to improve neurological transmissions within the brain resulting in reduction in fatigue, increased motivation, improved memory, and enhanced learning.[6]

    Mucuna Pruriens

    80 mg (>40% L-Dopa)

    L-Dopa, a compound from mucuna pruriens has been shown to improve motivation levels as well as increase libido and memory retention.[7]

    EGCG

    100 mg

    EGCG (from green tea extract) optimizes the efficiency of conversion of neurotransmitters in the brain while reducing the peripheral side effects on the body.[8]


    4 BRAIN VITAMINS


    Niacin

    40 mg (niacinamide)

    Also known as Vitamin B3, Niacin has brain boosting and anti-oxidative properties. It also plays a role in cellular communication.[9]

    Vitamin b6

    10 mg (pyridoxal 5’-phosphate)

    Vitamin B6 is an essential vitamin which is required for the conversion of several key neurotransmitters. We use P5P, one of the most bioactive forms of B6.[10]

    Vitamin b12

    200 mcg (methylcobalamin)

    B12 is an essential vitamin that is crucial for the synthesis of key neurotransmitters which correlate with our mood, energy, and stress levels.[11]

    Vitamin D3

    1000 IU (cholecalciferol)

    Vitamin D is essential for brain function and mood. This vitamin is involved in a wide array of bodily functions.[12]

    Unlock Your Mind's Full Potential


    metaFOCUS® is just one component of the optimal mental performance equation. Tap into your true potential and comprehensively upgrade your brain with metaBRAIN®, a three-supplement box designed for peak mental performance.


    Formulated with a collective 31 nootropic ingredients, the three supplements in the metaBRAIN® box complement each other, sharpening focus, enhancing memory recollection, and igniting drive.†

    Experience Intense FocusLaser-Sharp MemoryUnstoppable Drive.


    Upgrade Your Brain, Upgrade Your Life.

    The metaBRAIN® box includes "Upgrade Your Brain, Upgrade Your Life", a 16-page booklet that contains a comprehensive supplementation protocol based on your body-weight and cognitive requirements.


    The booklet also introduces the branches for an upgraded life, which includes 16 foundational habits you can practice to reach your peak human potential—for both beginner and more experienced biohackers.

    METABRAIN® IS Designed to Optimize All Areas Of Brain Function†

    Patents & Trademarks

    Cognizin® is a registered trademark of KYOWA HAKKO BIO CO., LTD.

    SerinAid® is a registered trademark of Chemi Nutra. SerinAid is protected under U.S. patent numbers 5,700,668, 6,492,146, 6,645,742, 6,673,378, and 8,124,594. 

    References

    [1] Abel, Ted, and Peter V Nguyen. “Regulation of hippocampus-dependent memory by cyclic AMP-dependent protein kinase.” Progress in brain researchvol. 169 (2008): 97-115. doi:10.1016/S0079-6123(07)00006-4

    [2] Lepski, Guilherme et al. “cAMP promotes the differentiation of neural progenitor cells in vitro via modulation of voltage-gated calcium channels.” Frontiers in cellular neuroscience vol. 7 155. 19 Sep. 2013, doi:10.3389/fncel.2013.00155

    [3] Loots DT, Mienie LJ, Bergh JJ, Van der Schyf CJ. Acetyl-L-carnitine preventstotal body hydroxyl free radical and uric acid production induced by1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the rat. Life Sci. 2004Jul 23;75(10):1243-53. PubMed PMID: 15219812. 

    [4] Glade MJ, Smith K. Phosphatidylserine and the human brain. Nutrition. 2015Jun;31(6):781-6. doi: 10.1016/j.nut.2014.10.014. Epub 2014 Nov 4. Review. PubMedPMID: 25933483.

    [5] Mashayekh, Ameneh et al. “Effects of Ginkgo biloba on cerebral blood flow assessed by quantitative MR perfusion imaging: a pilot study.” Neuroradiology vol. 53,3 (2011): 185-91. doi:10.1007/s00234-010-0790-6

    [6] Lou HC. Dopamine precursors and brain function in phenylalanine hydroxylasedeficiency. Acta Paediatr Suppl. 1994 Dec;407:86-8. Review. PubMed PMID: 7766968.

    [7] Fioravanti, Mario, and Ann E Buckley. “Citicoline (Cognizin) in the treatment of cognitive impairment.” Clinical interventions in aging vol. 1,3 (2006): 247-51. doi:10.2147/ciia.2006.1.3.247

    [8] Packer, Lester, and Enrique Cadenas. “Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling.” Journal of clinical biochemistry and nutrition vol. 48,1 (2011): 26-32. doi:10.3164/jcbn.11-005FR

    [9] Kennedy, David O. “B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review.” Nutrients vol. 8,2 68. 27 Jan. 2016, doi:10.3390/nu8020068

    [10] Mashayekh, Ameneh et al. “Effects of Ginkgo biloba on cerebral blood flow assessed by quantitative MR perfusion imaging: a pilot study.” Neuroradiology vol. 53,3 (2011): 185-91. doi:10.1007/s00234-010-0790-6

    [11] Lou HC. Dopamine precursors and brain function in phenylalanine hydroxylasedeficiency. Acta Paediatr Suppl. 1994 Dec;407:86-8. Review. PubMed PMID: 7766968.

    [12] Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Glutamate Receptors. Available from: https://www.ncbi.nlm.nih.gov/books/NBK10802/

    [13] Yarotskyy V, Glushakov AV, Sumners C, Gravenstein N, Dennis DM, Seubert CN,Martynyuk AE. Differential modulation of glutamatergic transmission by3,5-dibromo-L-phenylalanine. Mol Pharmacol. 2005 May;67(5):1648-54. Epub 2005 Feb1. PubMed PMID: 15687225.

    [14] Hasselmo, Michael E. “The role of acetylcholine in learning and memory.” Current opinion in neurobiology vol. 16,6 (2006): 710-5. doi:10.1016/j.conb.2006.09.002

    [15] Kobayashi S, Iwamoto M, Kon K, Waki H, Ando S, Tanaka Y. Acetyl-L-carnitineimproves aged brain function. Geriatr Gerontol Int. 2010 Jul;10 Suppl 1:S99-106.doi: 10.1111/j.1447-0594.2010.00595.x. PubMed PMID: 20590847.

    [16] McGlade E, Agoston AM, DiMuzio J, Kizaki M, Nakazaki E, Kamiya T, Yurgelun-Todd D. The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males. J Atten Disord. 2019 Jan;23(2):121-134. doi: 10.1177/1087054715593633. Epub 2015 Jul 15. PubMed PMID: 26179181.

    [17] Food and Nutrition Sciences et al. "Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women" 2012, 3, 769-773. doi:10.4236/fns.2012.36103 Published Online June 2012

    [18] Hellhammer, Juliane et al. “A soy-based phosphatidylserine/ phosphatidic acid complex (PAS) normalizes the stress reactivity of hypothalamus-pituitary-adrenal-axis in chronically stressed male subjects: a randomized, placebo-controlled study.” Lipids in health and disease vol. 13 121. 31 Jul. 2014, doi:10.1186/1476-511X-13-121

    [19] Roiser, Jonathan P et al. “The subjective and cognitive effects of acute phenylalanine and tyrosine depletion in patients recovered from depression.” Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol. 30,4 (2005): 775-85. doi:10.1038/sj.npp.1300659

    [20] Jäger, Ralf et al. “The effect of phosphatidylserine on golf performance.” Journal of the International Society of Sports Nutrition vol. 4 23. 4 Dec. 2007, doi:10.1186/1550-2783-4-23

    [21] Di Cesare Mannelli L, Vivoli E, Salvicchi A, Schiavone N, Koverech A, MessanoM, Nicolai R, Benatti P, Bartolini A, Ghelardini C. Antidepressant-like effect ofartemin in mice: a mechanism for acetyl-L-carnitine activity on depression.Psychopharmacology (Berl). 2011 Nov;218(2):347-56. doi:10.1007/s00213-011-2326-0. Epub 2011 May 18. PubMed PMID: 21590285.

    [22] Aliev, Gjumrakch et al. “Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.” Journal of cellular and molecular medicine vol. 13,2 (2009): 320-33. doi:10.1111/j.1582-4934.2008.00324.x

    [23] Salehi, Bahare et al. “Insights on the Use of α-Lipoic Acid for Therapeutic Purposes.” Biomolecules vol. 9,8 356. 9 Aug. 2019, doi:10.3390/biom9080356

    [24] Wang, Huimin et al. “Ameliorating effect of luteolin on memory impairment in an Alzheimer's disease model.” Molecular medicine reports vol. 13,5 (2016): 4215-20. doi:10.3892/mmr.2016.5052

    [25] Ma, Nan et al. “Exchange protein activated by cAMP enhances long-term memory formation independent of protein kinase A.” Learning & memory (Cold Spring Harbor, N.Y.) vol. 16,6 367-70. 23 May. 2009, doi:10.1101/lm.1231009